Genes Found for Preventing Hypoxia

Resistance to hypoxia, ie oxygen-less air condition, it is controlled by key genes hypoxia-inducible factor-1 alpha. Durability is different between one individual and another individual. Exercise face less oxygen conditions (hypoxia) in a controlled and repeatable brain can increase resilience to face less severe and fatal oxygen. This training will give a positive effect in real conditions when pilots fly planes they flew and prevent heart attacks and strokes.Similarly, exposure to Lt. Col. Dr. Henry Mulyawan in his doctoral dissertation entitled "Analysis of Adaptive Response Network Brain Pascainduksi Hipoksis Intermittent Hipobarik in Mice: Special Study on Expression of hypoxia-inducible factor-1 alpha"."Based on this research, it is possible to do the selection of pilots for pilots are genetically superior in hypoxic conditions," he said. Exercise repeated in room hipobarik can hone their resilience to events at a certain altitude less oxygen that can occur at any time, either in the military and civilian aviators.In a session led by Dr. Dr. Siti Setiati, SpPD, Secretary of the Faculty of Medicine, University of Indonesia (Faculty of medicine), Tuesday (1/10/2011), Henry, lecturer at the Faculty of medicine Flight Neuroscience, Biomedical Sciences doctoral degree with honors cum laude (GPA 3 , 93). Submission of dissertation promoted by Prof. Dr. Mohamad Sadikin, DSc. Test team headed by Prof. Dr. RM Padmosantjojo, SpBS.In the induction of hypoxia is known to occur hipobarik repair brain tissue damage and an increased number of new blood vessels in the brain cortex. "That's due to factor genes that protect the brain damage caused by exposure to hypoxia hipobarik," said Henry.Hipobarik under physiological conditions will be further examined by looking at its effect on humans. The research was conducted at room hipobarik to learn while improving the durability of the fighter pilots hipobarik pressure and gravity.For civil aviation pilots, the training aims to provide physical endurance to live a long distance flight to 15 hours without stopping. Physiological impacts experienced not only pilots, but also because of the altitude passenger miles from 1.5 to 2.4 mild oxygen deprivation could potentially occur on flights that take a long time.The cause of the accidentEffects of hypoxia hipobarik experienced pilots flying into the cause of the crash, among others, in the United States (1999 and 2003), Australia (2000 and 2008), and Greece (2005). Authorities linked the United States reported 11 incidents decompression (decrease in air pressure in the cabin) on commercial aircraft every 50,000 flying hours."In hypoxic conditions, cabin crew unwittingly experiencing lack of oxygen to the brain is fatal. This is what started the tragic plane crash, "said Henry.To prevent a potentially fatal condition, it needs regular training in hipobarik space for military and civilian aviators to resist exposure to oxygen is less acute conditions.Henry did some research for nearly four years on a low-pressure air chamber (chamber hipobarik) in Health Institute of Aeronautics and Space Air Force Dr. Saryanto. Laboratory testing of samples carried out at Faculty of medicine and the Eijkman Institute for Molecular Biology